A study of the kinematics and binary-induced shaping of the planetary nebula HaTr 4

We present the first detailed spatio-kinematical analysis and modelling of the planetary nebula HaTr 4, one of few known to contain a post-common-envelope central star system. Common envelope evolution is believed to play an important role in the shaping of planetary nebulae, but the exact nature of this role is yet to be understood. High spatial- and spectral- resolution spectroscopy of the [OIII]5007 nebular line obtained with VLT-UVES are presented alongside deep narrowband Ha+[NII]6584 imagery obtained using EMMI-NTT, and together the two are used to derive the three-dimensional morphology of HaTr 4. The nebula is found to display an extended ovoid morphology with an enhanced equatorial region consistent with a toroidal waist - a feature believed to be typical amongst planetary nebulae with post-common-envelope central stars. The nebular symmetry axis is found to lie perpendicular to the orbital plane of the central binary, concordant with the idea that the formation and evolution of HaTr 4 has been strongly influenced by its central binary.Comment: 9 pages, 5 figures, accepted for publication in MNRA

The Ubiquitous 'c': from the Stefan-Boltzmann Law to Quantum Information

I discuss various aspects of the role of the conformal anomaly number c in 2- and 1+1-dimensional critical behaviour: its appearance as the analogue of Stefan's constant, its fundamental role in conformal field theory, in the classification of 2d universality classes, and as a measure of quantum entanglement, among other topics.Comment: 8 pages, 2 figures. Boltzmann Medal Lecture, Statphys24, Cairns 2010. v3: minor revision

The post-common-envelope, binary central star of the planetary nebula Hen 2-11

We present a detailed photometric study of the central star system of the planetary nebula Hen 2-11, selected for study because of its low-ionisation filaments and bipolar morphology - traits which have been strongly linked with central star binarity. Photometric monitoring with NTT-EFOSC2 reveals a highly irradiated, double-eclipsing, post-common-envelope system with a period of 0.609 d. Modelling of the lightcurve indicates that the nebular progenitor is extremely hot, while the secondary in the system is probably a K-type main sequence star. The chemical composition of the nebula is analysed, showing Hen 2-11 to be a medium-excitation non-Type I nebula. A simple photoionisation model is constructed determining abundance ratios of C/O and N/O which would be consistent with the common-envelope cutting short the AGB evolution of the nebular progenitor. The detection of a post-common-envelope binary system at the heart of Hen 2-11 further strengthens the link between binary progeny and the formation of axisymmetric planetary nebulae with patterns of low-ionisation filaments, clearly demonstrating their use as morphological indicators of central star binarity.Comment: Accepted for publication in A&A. 9 pages, 5 figures, 4 table

Trial design: how must we move ahead?

Scleroderma is clinically heterogeneous and a variety of plausible mechanisms of disease have been hypothesized. Recent years have witnessed a significant improvement in overall survival although all of the gains in management have been therapies for specific organ involvement, e.g. renal crisis and pulmonary arterial hypertension. Future studies will rely on improved clinical science, which involves structured validation of proposed measures of outcome; development of a combined response index; and further refinement of specific subsets of disease expression. Immunoablation with stem cell reconstitution is an example of aggressive therapy chosen as appropriate for a particularly severe disease subset and in whom the pilot data are encouraging. Good science and clinical ethics force continued consideration of equipoise between risk and benefi

Swine Producer Appraisal of the Community Assessment Model for Odor Dispersion (CAM)

The community assessment model (CAM) for odor dispersion is a tool to assist in the siting of swine production facilities. CAM considers the size and type of a swine production system, local historical weather conditions, and odor control implementation. It predicts the number of hours of exposure to various levels of odor, by month, for each receptor in a given community. A follow-up survey of all CAM users since 2005 was conducted. The survey was designed to provide: 1) formative feedback for programming adjustments to improve Extension efficiency, usability, and reduce costs; and 2) summative feedback used to provide an indirect baseline assessment of the broader impact that CAM has had on reducing odor-related conflict. For the majority of producers who used CAM, the potential impacts to their neighbors factored heavily into decisions. CAM was believed to be very important to the siting process. A high majority (95%) of producers clearly understood the model results. Over half communicated these results to their neighbors where a third of these were considered positive interactions. Overall, for producers who went on to build at sites that were modeled there was a significant improvement in neighbor relations. CAM continues to evolve as a tool, with the addition of more refined odor dispersion parameters and the ability to include cattle and poultry. The state of Iowa has passed legislation that would, when funding is made available, integrate the use of CAM into odor management policy

OH yields from the CH3CO+O-2 reaction using an internal standard

Laser flash photolysis of CH3C(O)OH at 248 nm was used to create equal zero time yields of CH3CO and OH. The absolute OH yield from the CH3CO + O2 (+M) reaction was determined by following the OH temporal profile using the zero time OH concentration as an internal standard. The OH yield from CH3CO + O2 (+M) was observed to decrease with increasing pressure with an extrapolated zero pressure yield close to unity (1.1 ± 0.2, quoted uncertainties correspond to 95% confidence limits). The results are in quantitative agreement with those obtained from 248 nm acetone photolysis in the presence of O2

Platelet lysate as a serum substitute for 2D static and 3D perfusion culture of stromal vascular fraction cells from human adipose tissue

Fetal bovine serum (FBS) and fibroblast growth factor (FGF)-2 are key supplements for the culture of stromal vascular fraction (SVF) cells from adipose tissue, both for typical monolayer (2D) expansion and for streamlined generation of osteogenic-vasculogenic grafts in 3D perfusion culture. The present study investigates whether factors present in human platelet lysate (PL) could substitute for FBS and FGF-2 in 2D and 3D culture models of SVF cells from human lipoaspirates. SVF cells were grown in medium supplemented with 10% FBS+FGF-2 or with 5% PL. In 2D cultures, PL initially supported SVF cell proliferation, but resulted in growth arrest shortly after the first passage. Freshly isolated SVF cells cultured with both media under perfusion for 5 days within 3D ceramic scaffolds induced bone formation after subcutaneous implantation in nude mice. However, blood vessels of donor origin were generated only using FBS+FGF-2-cultured cells. This was unexpected, because the proportion of CD34+/CD31+ endothelial lineage cells was significantly higher with PL than that of FBS+FGF-2 (33% vs. 3%, respectively). These results support the use of PL as a substitute of FBS+FGF-2 for short-term culture of human SVF cells, and indicate that more specific serum-free formulations are required to maintain a functionally vasculogenic fraction of SVF cells expanded under 3D perfusion